Last edited by Tacage
Wednesday, August 12, 2020 | History

6 edition of Cell cycle regulation and differentiation in cardiovascular and neural systems found in the catalog.

Cell cycle regulation and differentiation in cardiovascular and neural systems

by Giordano, Antonio MD

  • 168 Want to read
  • 34 Currently reading

Published by Springer in New York .
Written in English

    Subjects:
  • Heart,
  • Nervous System Physiological Phenomena,
  • Cell Differentiation,
  • Regulation,
  • Cell cycle,
  • Central nervous system,
  • Differentiation,
  • Cell Cycle,
  • Physiology,
  • Cardiovascular Physiological Phenomena

  • Edition Notes

    Includes bibliographical references and index.

    Statementedited by Antonio Giordano, Umberto Galderisi
    Classifications
    LC ClassificationsQH604 .C4415 2010
    The Physical Object
    Paginationxi, 256 p. :
    Number of Pages256
    ID Numbers
    Open LibraryOL25328743M
    ISBN 10160327152X, 1603271538
    ISBN 109781603271523, 9781603271530
    LC Control Number2010931606
    OCLC/WorldCa688679700

      NR2F2 (nuclear receptor subfamily 2, group F, member 2) is necessary for neural differentiation in human ESCs. Oct4 and miR can form a regulation loop during neural differentiation by interacting with NR2F2. The function of miRNAs in neural differentiation is illustrated in Additional file 3. Introduction. The differentiation of embryonic stem cells (ESCs) in vitro is a powerful system for identifying developmental cues required for lineage commitment. Like their in vivo counterparts, the cells of the inner cell mass of the blastocyst, ESCs can self-renew and differentiate into all three adult germ layers. Maintenance of pluripotency and self-renewal depends on the expression of.

      The role of the cell cycle as an inhibitor of the late stages of cellular differentiation is well known, but in early embryonic development its role is mysterious. Normally, embryonic stem (ES) cells proliferate quickly during differentiation and do not differentiate simply by cell cycle slowing. In this paper, it is shown that the role of the cell cycle in terminal stages of differentiation.   Genetic analysis has revealed that the dual specificity protein kinase DYRK1A has multiple roles in the development of the central nervous system. Increased DYRK1A gene dosage, such as occurs in Down syndrome, is known to affect neural progenitor cell differentiation, while haploinsufficiency of DYRK1A is.

    Activin/Nodal growth factors control a broad range of biological processes, including early cell fate decisions, organogenesis and adult tissue homeostasis. Here, we provide an overview of the mechanisms by which the Activin/Nodal signalling pathway governs stem cell function in these different stages of development. We describe recent findings that associate Activin/Nodal signalling to. Cell Cycle Regulation. Cell proliferation is strictly regulated Unregulated/abnormal proliferation is oncogenesis or Cancer An overview of the cell-cycle control system. Cell Cycle- External Regulators. Cell replacement in different tissues regulated by growth factors; can be specific for specific cell types; Growth Factors and Cell Cycle Progress.


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Cell cycle regulation and differentiation in cardiovascular and neural systems by Giordano, Antonio MD Download PDF EPUB FB2

In Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems Antonio Giordano, Umberto Galderisi and a panel of the most respected authorities in their field offer an in-depth analysis of the differentiation process in two systems that have profound relationships with one another.

The text looks at several aspects of the Format: Hardcover. In Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems Antonio Giordano, Umberto Galderisi and a panel of the most respected authorities in their field offer an in-depth analysis of the differentiation process in two systems that have profound relationships with one another.

Ground-breaking and authoritative, Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems is a must have for all researchers in cardiovascular medicine and neuroscience and will prompt the scientific community to perceive cell cycle regulation and differentiation under a novel and more comprehensive light.

ISBN: X OCLC Number: Description: xi, pages: illustrations: Contents: Short introduction to the cell cycle --The basic helix-loop-helix transcription factors in neural differentiation --Transcription factors and muscle differentiation --The neural stem cells --Cardiac stem and progenitor cells --Muscle stem cells.

Complex physiopathological relationships have been proven to exist between two of the body's most vital organs; the brain and the heart. In Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems Antonio Giordano, Umberto Galderisi and a panel of the most respected authorities in their field offer an in-depth analysis of the differentiation process in two systems that.

Cell cycle regulation and differentiation. G 1 /S cyclin/CDK complexes and some of the proteins involved in their regulation are depicted in the picture. Ink4. In: Giordano A., Galderisi U. (eds) Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems.

Springer, New York, NY First Online 15 July   When monolayers of hiPSCs are 85–90% confluent, cardiac differentiation were performed. For the cell-suspension system, the hiPSCs were dissociated, suspended in mTeSR1 medium supplemented with.

The ubiquitin E3 ligase RNF and its co-factor ZC4H2 are required for multiple neural developmental processes through different targets, including spinal cord patterning and the development of the cerebellum and the locus coeruleus.

Here, we explored the effects of loss of ZC4H2 and RNF on the proliferation and differentiation of neural stem cells (NSCs) derived from mouse embryonic cortex. Stefano Pluchino, Marco Bacigaluppi, Elena Brini, Erica Butti, Chiara Cossetti, Melania Cusimano, Lucia Zanotti, Gianvito Martino, The Neural Stem Cells, Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems, /, (), ().

Embryonic neural stem cell (NSC)-transplantation or endogenous NSC-activation is a recent challenging approach for the treatment of neurological diseases or injuries to the central nervous system (CNS) [1–3].NSCs comprise most of the progenitor cells (PCs) in the CNS [4,5] and are capable of self-renewal and multipotent differentiation into the three cell types of the CNS (neurons.

We expected pathways related to differentiation signals or cell cycle control to be downregulated, but most differentially expressed genes found were genes related to oxygen sensing (egln2), reduction-oxidation (redox) process (rdh8a), and mitochondria metabolism (rmnd1 and abat) (Figures 7F and 7G).

Thus, the first transcriptional response to. Genes associated with cell cycle regulation and the p53 signaling pathway were then investigated, to determine whether μg reduced cell proliferation and increased apoptosis or cell cycle arrest (Fig.

In control/1xg conditions, stem cells differentiated into EBs showed downregulation of cell cycle genes possibly associated with differentiation.

Allow cell to exit mitosis and return to interphase next cell cycle cyclin B-CDC2 acts as M phase-promoting factor (MPF) activate other proteins through phosphorylation. 1. Introduction. The cellular basis of neurogenesis consists of neural stem/progenitor cells (NSCs/NPCs).

NSCs are undifferentiated precursors that retain the ability to proliferate and self-renew while being able to differentiate into the three major neural lineages: neurons, astrocytes, and oligodendrocytes [].Accumulative evidence has supported the critical roles of NSC proliferation and.

Muscarinic acetylcholine receptors involved in the regulation of neural stem cell proliferation and differentiation in vitro Chang Zhou Department of Biological Science and Biotechnology, Tsinghua University, State Key Laboratory of Biomembranes, BeijingChina.

Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems - Antonio Giordano - Hardcover - english - This includes neural stem cell proliferation, specification, determination, and differentiation in embryonic, postnatal, and adult systems. Also reviewed are studies of the initiation and regulation of the cell cycle in the nervous system, transcriptional and translational regulation of early gene expression, and epigenetic regulation in the.

from book Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems (pp) Chapter July with 12 Reads How we measure 'reads'.

A strong connection exists between the cell cycle and mechanisms required for executing cell fate decisions in a wide-range of developmental contexts. Terminal differentiation is often associated with cell cycle exit, whereas cell fate switches are frequently linked to cell cycle transitions in dividing cells.

These phenomena have been investigated in the context of reprogramming. Cell Cycle Regulation and Differentiation in Cardiovascular and Neural Systems and Publisher Springer. Save up to 80% by choosing the eTextbook option for ISBN:The print version of this textbook is ISBN:Amanda J.

Barlow, in Neural Crest Cells, ENCC Differentiation Within the Gut Wall. Neuronal differentiation of ENCC begins early during mouse embryonic development while ENCC are migrating along the small intestine and continues into postnatal life [,].Several factors expressed within the gut mesenchyme have been shown to induce differentiation of ENCC into neurons, including Gdnf.Ensembl ENSG ENSMUSG UniProt Q Q RefSeq (mRNA) NM_ NM_ RefSeq (protein) NP_ NP_ Location (UCSC) Chr 6: – Mb Chr – Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Transcription factor SOX-4 is a protein that in humans is encoded by the SOX4 gene.

Contents 1 Function 2 Clinical .